Cytochrome P4501A induction in oil-exposed pink salmon Oncorhynchus gorbuscha embryos predicts reduced survival potential
نویسندگان
چکیده
Cytochrome P4501A (CYP1A) induction in pink salmon Oncorhynchus gorbuscha embryos exposed to crude oil is linked to adverse effects at cellular, organism and population levels, and can be used to predict these responses. When combined with the results of an experiment designed to examine CYP1A induction during embryonic stages and growth after emergence, results from a series of experiments spanning 4 other brood years demonstrated that CYP1A induction is related to a variety of lethal and sublethal effects, including poorer marine survival, reduced growth and abnormalities. The lowest observed effective concentration of total polynuclear aromatic hydrocarbons (TPAH) in water that caused significant physiological responses, including reduced size 6 mo after exposure ended (<0.94 μg l–1), was less than the lowest concentration that caused significant CYP1A induction (<3.7 μg l–1). Thus, CYP1A induction is not only a biomarker, it can be considered a bioindicator; induction in early life stages implies long-term negative consequences for the individual and the population.
منابع مشابه
SENSITIVITY OF FISH EMBRYOS TO WEATHERED CRUDE OIL: PART II. INCREASED MORTALITY OF PINK SALMON (<i>ONCORHYNCHUS GORBUSCHA</i>) EMBRYOS INCUBATING DOWNSTREAM FROM WEATHERED <i>EXXON VALDEZ</i> CRUDE OIL
We incubated pink salmon embryos under three exposure conditions, direct contact with oil-coated gravel, effluent from oil-coated gravel, and direct contact with gravel coated with very weathered oil (VWO). Embryo mortalities and polynuclear aromatic hydrocarbon (PAH) accumulation in embryo tissues during the direct-contact and effluent exposure experiments were not significantly different, ind...
متن کاملAssessment of the genetic toxicological impacts of the Exxon Valdez oil spill on pink salmon (Oncorhynchus gorbuscha) may be confounded by the influence of hatchery fish.
متن کامل
Evidence of Olfactory Imprinting at an Early Life Stage in Pink Salmon (Oncorhynchus gorbuscha)
Pacific salmon (Oncorhynchus spp.) navigate towards spawning grounds using olfactory cues they imprinted on as juveniles. The timing at which imprinting occurs has been studied extensively, and there is strong evidence that salmon imprint on their natal water during the parr-smolt transformation (PST). Researchers have noted, however, that the life histories of some species of Pacific salmon co...
متن کاملGenetic analysis of duplicate malate dehydrogenase loci in the pink salmon, Oncorhynchus gorbuscha.
The results of breeding experiments with the pink salmon, Oncorhynchus gorbuscha, indicate that s-MDH-A and s-MDH-B subunits are each encoded by duplicate loci. Limited evidence suggests also that the two loci encoding for the s-MDH-A subunit are each polymorphic and linked or pseudolinked.
متن کاملImpact of the Oil Spill on Juvenile Pink and Chum Salmon and Their Prey in Critical Nearshore Habitats
The objective of this study was to determine the impact of the Exxon Valdez oil spill on juvenile pink and chum salmon during their initial period of residency in nearshore marine habitats of western Prince William Sound. In oiled locations, both pink and chum salmon fry in the nearshore marine environment were contaminated by hydrocarbons in 1989, but not in 1990. Field observations and labora...
متن کامل